This sheet pan pork tenderloin bakes to perfection in 35 short minutes, topped with a simple but delicious maple-mustard sauce. Surrounding it are tender, caramelized Brussels sprouts and sweet butternut squash.

Sheet pan dinners are an easy way to make a full meal in one fell swoop. Just combine your meat (chicken, pork, beef, tofu, fish) with chopped vegetables that have a similar cooking time on a rimmed baking sheet, toss with oil, salt, pepper, and any other flavorings you like, pop the pan in the oven and wait for the timer to ding—dinner’s ready!

Baked pork tenderloin is one of my ideal weeknight meats because it’s quick to cook (35 minutes), naturally tender, and its mild flavor means it can go with just about any flavoring. Even with simple olive oil, salt, and pepper, it’s great! But to add a little more flavor—with minimal effort and mess—I like to stir together pure maple syrup and spicy, grainy mustard and use that as a quick sauce for the pork. Maple and mustard pair so well, especially for a comforting fall/winter meal. A note about mustard: I prefer to use grainy brown mustard (you’ll see it labelled “spicy brown mustard” in stores) but any kind you like will work.
Optional: Marinate the pork for extra flavor. Combine the pork and maple-mustard mixture in gallon-sized plastic bag, press as much air out of the bag as you can, and seal it. Turn the bag a few times to coat the pork on all sides. Refrigerate for 30 minutes and up to 24 hours. When you’re ready to cook, remove the pork from the bag, discarding the remaining liquid.

Other pork recipes you might like:
Pork Tenderloin with Ah So Sauce
Pork Tenderloin with Honey, Dijon and Apricot Preserves
Pork Tenderloin with BBQ Dry Rub
Sheet Pan Pork Tenderloin with Brussels Sprouts and Butternut Squash
Ingredients
- 1.5 to 2 lb pork tenderloin
- 2 cups brussels sprouts cut in half
- 1/2 large butternut squash peeled and cut into 1-inch cubes
- 2 tbsp olive oil
- 1 1/2 tbsp spicy brown mustard (or Dijon)
- 4 tbsp pure maple syrup
Instructions
- Optional: Marinate the pork for extra flavor. In a small bowl, stir together the mustard and maple syrup. Pour the maple-mustard mixture into a gallon-sized plastic bag, add the pork, press as much air out of the bag as you can, and seal it. Turn the bag a few times to coat the pork on all sides. Refrigerate for 30 minutes and up to 24 hours, turning the bag over occasionally. When you’re ready to cook, remove the pork from the bag, discarding the remaining liquid.
- Preheat the oven to 425 degrees F. Line a large rimmed baking sheet with foil.
- Scatter the brussels sprouts and squash on the baking sheet. Add the oil and toss to evenly coat the veggies. Season them liberally with salt and pepper.
- Move the veggies to make space for the pork in the center of the sheet pan and place the pork on the pan.
- In a small bowl, stir together the mustard and maple syrup. Pour over the pork, turning it over to coat both sides. (If you've marinated the pork, simply place the marinated tenderloin on the baking sheet.)
- Roast for about 35 minutes, until the internal temperature of the pork registers 145 degrees F on a thermometer. Transfer the pork to a cutting board and let rest for 5 to 10 minutes before slicing. Serve with the brussels sprouts and butternut squash.
Pingback: Sheet Pan Pork Tenderloin with Brussels Sprouts and Butternut Squash – Top News Park
Pingback: Sheet Pan Pork Tenderloin with Brussels Sprouts and Butternut Squash
Pingback: Sheet Pan Pork Tenderloin with Brussels Sprouts and Butternut Squash – Nilfat
Pingback: Sheet Pan Pork Tenderloin with Brussels Sprouts and Butternut Squash – GOTWEIGHT
Pingback: Sheet Pan Pork Tenderloin with Brussels Sprouts and Butternut Squash - gobeautyandhealthtips.com
Pingback: Pan leaf pork tenderloin with brussels sprouts and pumpkin - TOP HEALTH LINK
Pingback: Sheet Pan Pork Tenderloin with Brussels Sprouts and Butternut Squash - Wellnesslance
Pingback: Sheet Pan Pork Tenderloin with Brussels Sprouts and Butternut Squash - fitnessandhealth2021.com
Pingback: Sheet Pan Pork Tenderloin with Brussels Sprouts and Butternut Squash - Desi Creator
So scrumptious
Pingback: Sheet Pan Pork Tenderloin with Brussels Sprouts and Butternut Squash – mayorprint.com
Pingback: Sheet Pan Pork Tenderloin with Brussels Sprouts and Butternut Squash – Enhance
Pingback: Sheet Pan Pork Tenderloin with Brussels Sprouts and Butternut Squash – EmeFx
Pingback: Sheet Pan Pork Tenderloin with Brussels Sprouts and Butternut Squash – Reduce Fat
Pingback: Sheet Pan Pork Tenderloin with Brussels Sprouts and Butternut Squash - Universal Online Prescriptions
Pingback: Sheet Pan Pork Tenderloin with Brussels Sprouts and Butternut Squash – Community share free everything
Pingback: Sheet Pan Pork Tenderloin with Brussels Sprouts and Butternut Squash – WEIGHT LOSS HEALTH AND FITNESS
Pingback: Sheet Pan Pork Tenderloin with Brussels Sprouts and Butternut Squash - Easymeals
Pingback: Sheet Pan Pork Tenderloin with Brussels Sprouts and Butternut Squash - DietTips
Pingback: Sheet Pan Pork Tenderloin with Brussels Sprouts and Butternut Squash – Lady in Rainbow
nice post
Pingback: Sheet Pan Pork Tenderloin with Brussels Sprouts and Butternut Squash – CBD News24
I’ve been working out regularly and I watch my food intake but I keep gaining weight and it’s because of our hormonal imbalance (stress is a very big factor) not because we are not doing anything about it. It ishttps://oke.io/px6kKvRN
i agree…
nice post , thanks for sharing this info
Hi. I will follow you because what you share is extremely helpful to me. Hope you continue to thrive.
Pingback: Filet de porc poêlé aux choux de Bruxelles et à la courge musquée - scoopcorner
I just made this last night and it was a hit! This recipe is definitely a keeper! Excited to try other recipes of yours. :)
Pingback: Flat pork loin with Brussels sprouts and butternut squash - LabWelness
Pingback: Pan-fried Pork Tenderloin with Brussels Sprouts and Butternut Squash - Simo Baha
Pingback: Sheet Pan Pork Tenderloin with Brussels Sprouts and Butternut Squash - Quick Weight Loss1
Pingback: Sheet pan pork tenderloin with Brussels sprouts and butternut squash - Meyild01
Pingback: Sheet Pan Pork Tenderloin with Brussels Sprouts and Butternut Squash - SlimReads.com
Pingback: Gebakken varkenshaas met spruitjes en pompoen - SCOOPCORNER
Pingback: Sheet Pan Pork Tenderloin with Brussels Sprouts and Butternut Squash – Health Track Hub